SOX after SOX: SOXession regulates neurogenesis
نویسندگان
چکیده
منابع مشابه
Sex, Sox, and splicing
ammalian sex-determining factors with homology to DNA binding proteins are required for splicing, according to a study by Paolo SassoneCorsi and coworkers at the Université Louis Pasteur (Strasbourg, France). Examination of high mobility group (HMG) domain containing SRY and Sox proteins demonstrated a surprising but clear association with splicing complexes. SRY, the testis-determining factor ...
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The Y chromosomal switch gene SRY, which initiates testis development during mammalian embryogenesis was recently described (l).The SRY-encoded protein contains a 79 amino acid DNA-binding motif referred to as an HMG-box (2) known to exist in other transcription factors or proteins involved in DNA bending (3). On the basis of the homology between their HMGboxes, other SRY-related genes have bee...
متن کاملA comparison of the properties of So Sox - 1 and Sox - 2
in of e n factor containing a 79-amino-acid DNA-binding domain known as the HMG box (Capel and Lovell-Badge, 1993). Many genes have now been cloned on the basis of their homology to the HMG box of Sry and comprise the Sox gene family, for Sry-related HMG box-containing genes. Approximately 20 Sox genes have been found in mammals, with more being identified in other vertebrates and invertebrates...
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We describe the identification and detailed expression pattern of a second Drosophila Sox gene, SoxNeuro (SoxN), highly related to mammalian group B Sox1, 2, 3 genes. SoxN is expressed in a highly dynamic pattern during embyogenesis, being associated with the development of the central nervous system (CNS), from the early steps onwards. We present strong evidence that the early SoxN neuroectode...
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NOTICE This technical report does not necessarily represent final EPA decisions or positions. It is intended to present technical analysis of issues using data that are currently available. The purpose in the release of such reports is to facilitate the exchange of technical information and to inform the public of technical developments which may form the basis for a final EPA decision, positio...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2011
ISSN: 0890-9369
DOI: 10.1101/gad.181487.111